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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATXN1 All Species: 18.79
Human Site: T280 Identified Species: 41.33
UniProt: P54253 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54253 NP_000323.2 815 86923 T280 H Q T M I P H T L T L G P P S
Chimpanzee Pan troglodytes XP_001170170 809 86155 T274 H Q T M I P H T L T L G P P S
Rhesus Macaque Macaca mulatta XP_001098366 689 73153 Q232 G R M P I Y Y Q M S R L P A G
Dog Lupus familis XP_545354 812 85486 T258 H Q T M I P H T L T L G P S P
Cat Felis silvestris
Mouse Mus musculus P54254 791 83775 T256 H Q T M I P H T L T L G P S S
Rat Rattus norvegicus Q63540 789 83482 T254 H Q T M I P H T L T L G P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509567 686 71870 M227 V D L T P G R M P V Y Y Q M S
Chicken Gallus gallus XP_425139 690 74081 T237 S G Y S G Y E T P T A G G N P
Frog Xenopus laevis NP_001121333 691 74939 E240 P V A Y P V N E M L L A C H S
Zebra Danio Brachydanio rerio NP_001038291 781 83267 Y238 P S Q V L V P Y T E S L L P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190485 925 98737 Q348 A R V S P F Q Q V S P V A Y R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 29.6 88 N.A. 86.9 87.3 N.A. 28.3 28.3 26.1 44 N.A. N.A. N.A. N.A. 24.5
Protein Similarity: 100 99.1 42.2 90.6 N.A. 89.6 89.6 N.A. 41.8 44.2 41.9 55.3 N.A. N.A. N.A. N.A. 36.6
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 93.3 N.A. 6.6 20 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 40 86.6 N.A. 93.3 93.3 N.A. 6.6 20 26.6 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 0 10 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 10 10 0 0 0 0 0 55 10 0 10 % G
% His: 46 0 0 0 0 0 46 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 10 0 10 0 0 0 46 10 55 19 10 0 0 % L
% Met: 0 0 10 46 0 0 0 10 19 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 19 0 0 10 28 46 10 0 19 0 10 0 55 28 19 % P
% Gln: 0 46 10 0 0 0 10 19 0 0 0 0 10 0 0 % Q
% Arg: 0 19 0 0 0 0 10 0 0 0 10 0 0 0 10 % R
% Ser: 10 10 0 19 0 0 0 0 0 19 10 0 0 28 55 % S
% Thr: 0 0 46 10 0 0 0 55 10 55 0 0 0 0 0 % T
% Val: 10 10 10 10 0 19 0 0 10 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 19 10 10 0 0 10 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _